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As CYP3A4 metabolizes about a quarter of all drugs, CBD may increase serum concentrations of www.doh.dc.gov. Drug Interaction Studies. 12 Cannabis can cause an acute increase in blood pressure (Frost et al 2013). Cannabis can  A sublingual application of CBD oil tincture may be the best way to take CBD for high blood pressure as it gets absorbed by the body fast, and the effects are f. Nov 20, 2018 CBD oil is a product created from cannabidiol, which is one of the many While these compounds and their interaction with the human body is complex, the these receptors and blood pressure, bone density, and inflammation. side effects associated with pharmaceutical pain medications, it can also be 

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